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Metabolic/Health RESET: GLP-1 Therapy for Weight Loss & Micro Dosing

What Is a Metabolic/Health RESET?

Our Metabolic/Health RESET Program is designed to restore metabolic balance, improve overall wellness, and support long-term health using physician-directed, science-based GLP-1 agonist therapy. The name reflects our belief that metabolic health is whole-body health. For some, this program functions as their medical weight-loss plan. For others, it targets other specific metabolic or neurocognitive conditions that respond well to GLP-1 therapy. Many patients benefit from both—addressing health concerns while also achieving healthy, sustainable weight loss.

What Is a GLP-1 Agonist?

GLP-1 agonists mimic the natural hormone GLP-1 (Glucagon-Like Peptide-1), produced in the gut and brain to regulate blood sugar, appetite, and neurotransmitter activity. GLP-1 medications have been used safely since 2010; newer generations offer greater effectiveness with fewer side effects.

Our program uses a compounded formulation of Tirzepatide (the active ingredient in Zepbound™/Mounjaro™), selected for its superior clinical outcomes and lower incidence of nausea. The compounded form allows personalized dose adjustment—rather than a fixed dose auto-injector.

How Do GLP-1 Medications Support Metabolic Health and Weight Loss?

  • Reduce appetite by calming appetite-regulating centers – quieting food noise
  • Improve insulin sensitivity for healthier blood sugar control
  • Maintain stable blood sugar levels—reducing crashes and cravings
  • Slow stomach emptying so you feel full longer

How Do GLP-1 Medications Help Conditions Beyond Weight?

Metabolic health influences nearly every organ system, including the brain. GLP-1 medications can therefore improve conditions not directly related to weight. Because the brain relies solely on glucose for fuel, stabilizing blood sugar can help stabilize mood, focus, and cognitive performance. Ongoing research shows improvements in mental and metabolic health, chronic inflammation, and long-term disease risk. GLP-1 medications have been shown to:

  • Stimulate new neuron formation
  • Improve neuron survival in the hippocampus—the brain’s center of memory, learning, emotion and stress regulation
  • Reduce neuroinflammation, a known driver of depression and other mental health conditions

Emerging evidence and clinical experience show potential beneficial effects on:

  • Depression, Anxiety
  • ADHD/ADD
  • Cognitive Decline
  • PCOS
  • Fatty Liver
  • Hyperlipidemia
  • Cardiac Disease
  • High Blood Pressure
  • Sleep Apnea

Additionally, many patients report reduced cravings for use of alcohol, nicotine, and other compulsive behaviors.

Optional Micro-Dosing of GLP-1 Medication

Some individuals respond best to starting at very low doses and titrating slowly. We’ll tailor your dosing schedule to ensure maximal comfort and success.  Micro-Dosing of GLP-1:

  • Allows the gut and appetite centers to adjust more comfortably
  • Minimizes nausea and digestive side effects
  • Helps those with sensitive digestion tolerate therapy more easily
  • Is ideal for patients seeking metabolic or mental-health benefits without significant weight loss

Healthy Habits for Maximum Success

While GLP-1 medications are powerful tools, they work best alongside healthy habits. It is important to remember:

  • It is CRITICAL to maintain a nutritious diet, including adequate protein to protect muscle mass during weight loss.
  • The recommended amount of protein per day is about 1 gram per pound of ideal (or goal) body weight.
  • Use protein shakes/smoothies if appetite suppression makes it challenging to consume adequate protein.
  • It is also CRITICAL to incorporate strength training into your weekly routine, to prevent loss of muscle tissue.

Side Effects – Minimal and Manageable

Tirzepatide is the GLP-1 associated with the least side effects. Most experience no adverse effects, or if so, they are usually mild, temporary, and manageable – nausea, vomiting, constipation, bloating, diarrhea, headache, fatigue.

A Chronic Condition Requires Long-Term Management

Excess body weight and the other medical indications for which the GLP-1 agonist can be beneficial are chronic medical conditions, so long-term therapy is most often required to maintain results. Stopping the GLP-1 typically results in regaining of weight and/or return of prior symptoms. Most are able to reduce their dose and/or frequency, once goal weight is reached. When micro-dosing has been effective, continuation of a minimal dose will likely continue being effective.

Who Should Not Use GLP-1 Agonists

GLP-1 medications are not recommended for those with history of Medullary Thyroid Cancer (MTC) or family history of Multiple Endocrine Neoplasia Type 2 (MEN 2), both rare conditions. GLP-1 agonists are contraindicated in pregnancy. Caution is advised for patients with a history of pancreatitis or gastroparesis – close monitoring would be indicated.

Metabolic/Health RESET – Schedule Your Consultation

  • During your initial physician visit, your health history, goals, and laboratory results will be reviewed.
  • You will receive a personalized plan that includes compounded Tirzepatide therapy.
  • A trained medical assistant will teach you to perform the simple subcutaneous injections.
  • Your first vial of Tirzepatide will be available immediately after your consultation.
  • We will provide you with all the necessary supplies for your therapy.

Through the Metabolic/Health RESET Program, our goal is to help you RESET how your body functions, RESET how you feel, and ENJOY renewed vitality through personalized, science-guided metabolic care.

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References for GLP-1 Therapy 

  1. Kim YK, Kim OY, Song J. Alleviation of Depression by Glucagon-Like Peptide 1 Through the Regulation of Neuroinflammation, Neurotransmitters, Neurogenesis, and Synaptic Function. Front Pharmacol. 2020 Aug 14;11:1270.
  2. Miller A, Joyce B, Bartelt K, Deckert J. Most GLP-1 Medications Correlated with a Lower Likelihood of Anxiety and Depression Diagnoses. Epic Research. https://epicresearch.org.
  3. Chia Siang Kow, et al. Efficacy and safety of GLP-1 receptor agonists in the management of obstructive sleep apnea in individuals without diabetes: A systematic review and meta-analysis of randomized, placebo-controlled trials. Sleep Medicine. 2025 May;129:40-44.
  4. Riedinger CJ, Sakach J, Maples JM, Fulton J, Chippior J, O’Donnell B, O’Malley DM, Chambers LM. Glucagon-like peptide-1 (GLP-1) receptor agonists for weight management: A review for the gynecologic oncologist. Gynecol Oncol. 2024 Nov;190:1-10.
  5. Odigwe C, Mulyala R, Malik H, Ruiz B, Riad M, Sayiadeh MA, Honganur S, Parks A, Rahman MU, Lakkis N. Emerging role of GLP-1 agonists in cardio-metabolic therapy – Focus on Semaglutide. Am Heart J Plus. 2025 Mar 1;52:100518.
  6. Lin, S., Deng, Y., Huang, J. et al.Efficacy and safety of GLP-1 receptor agonists on weight management and metabolic parameters in PCOS women: a meta-analysis of randomized controlled trials. Sci Rep 15, 16512 (2025).